Comparison of two commercial platforms and a laboratory developed test for detection of SARS-CoV-2 RNA. Mannonen L, Kallio-Kokko H, Loginov R, Jääskeläinen A, Jokela P, Antikainen J, et al. Comparison of two commercial molecular tests and a laboratory-developed modification of the CDC 2019-nCoV RT-PCR assay for the detection of SARS-CoV-2.
Moore NM, Li H, Schejbal D, Lindsley J, Hayden MK. Effectiveness of isolation, testing, contact tracing and physical distancing on reducing transmission of SARS-CoV-2 in different settings.
Kucharski AJ, Klepac P, Conlan A, Kissler SM, Tang M, Fry H, et al. WHO Overview of public health and social measures in the context of COVID-19. The relatively high false negative rates of SARS-CoV-2 RT-PCR testing need to be accounted for in clinical decision making, epidemiological interpretations, and when using RT-PCR as a reference for other tests. The clinical sensitivity of SARS-CoV-2 RT-PCR testing was only moderate at best. When also patients that were graded as high suspicion but never tested positive were included in the denominator, the sensitivity (95% CI) was: 67.5% (62.9-71.9%) inpatients 34.9% (31.4-38.5%) outpatients 47.3% (44.4-50.3%) all. The outpatient cohort of 1,814 individuals (mean age, 45.4 years 69.1% women) was sampled from epidemiological line lists by systematic quasi-random sampling. In addition to examining the first RT-PCR test of repeat-tested individuals, we also used high clinical suspicion for COVID-19 as the reference standard for calculating the sensitivity of SARS-CoV-2 RT-PCR.Īll 1,194 inpatients (mean age, 63.2 years 45.2% women) admitted to COVID-19 cohort wards during the study period were included. Adults who were clinically suspected of SARS-CoV-2 infection and underwent SARS-CoV-2 RT-PCR testing, with sufficient data in their medical records for grading of clinical suspicion were eligible. This population-based retrospective study was conducted in March-April 2020 in the Helsinki Capital Region, Finland. Our aim was to determine the real-life clinical sensitivity of SARS-CoV-2 RT-PCR. There are 4 types of acceleration: none, linear, exponential, and stepwise.Understanding the false negative rates of SARS-CoV-2 RT-PCR testing is pivotal for the management of the COVID-19 pandemic and it has implications for patient management. Polling rate is a measure of how often the mouse hardware reports changes to the PC.Ĭm/360 is the physical distance across one's mousepad that the mouse must travel in order to execute a perfect 360 turn in game. DPI, dots per inch, is an often used alternate acronym stolen from printer resolutions meaning the same thing in this context. There is also a tool, KovaaK's sensitivity matcher, which will allow you to manually determine and test sensitivities between games ( how?).ĬPI, or counts per inch, is a measurement of how many units of movement the mouse will report if you move it one inch. There's a site, mouse-sensitivity, that will allow you to convert one game's sensitivity settings into approximately equivalent settings in another game. Unfortunately, mouse sensitivity isn't standardized across games. A more calculated approach to finding your perfect sensitivity can be found in this video. One of our most skilled players recommends a sensitivity such that dragging your mouse all the way across your mousepad results in a perfect 360 in game.
The most popular way to do that is to just fiddle with the sensitivity slider until it "feels good". The goal should be to find the sensitivity that is right for you.
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